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A cell-permeable, potentiator of CFTR that directly, reversibly, and allosterically binds to WT and G551D mutant forms (≈10 μM) and increases the open probability to restore lung function.
The NF-κB Activation Inhibitor, also referenced under CAS 545380-34-5, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
The Cathepsin K Inhibitor III controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
The Phosphatase Inhibitor Cocktail Set II, Lyophilized controls the activity of Phosphatase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Thermo Scientific™ CaptureSelect™ tPA Ligand Leakage ELISA is designed to detect possible leached ligand of tissue plasminogen activator (tPA) purified using CaptureSelect tPA Affinity Matrix.
A cell permeable analog of curcumin that acts as a specific inhibitor of JAK2 (≈5 μM) and blocks STAT3 phosphorylation in MDA-MB-231 and PANC-1 cancer cells.
A cell-permeable hydrazone compound that reversibly binds eukaryotic translation initiation factor 4E (eIF4E; KD = 25μM) and disrupts eIF4E/eIF4G, but not eIF4E/4E-BP1, complex format
InSolution™ Y-27632 is a 10mm solution in DMSO. A highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140nM for p160ROCK).
The Calmodulin Inhibitory Peptide controls the biological activity of Calmodulin. This small molecule/inhibitor is primarily used for Cell Signaling applications.